|
KMID : 0365819740140010197
|
|
Journal of Pusan Medical College
1974 Volume.14 No. 1 p.197 ~ p.203
|
|
|
Studies on Lysozyme Activity of Various Organs of Rats Infected with Colnorchis sinensis
|
|
|
|
|
Abstract
|
|
|
The author investigated lysozyme activity of rats infected with 50, 100, and 200 metacercariae of Clonorchis sinensis. The metacercariae of Clonorchis sinensis were isolated from the Pseudorasbora parva by digestion technic.
The experimental animals were periodically sacrified by cut out of bilateral carotid arteries, on the 10th, 20th, 30th, 40th, and 50th day after infection.
The changes of lysozyme activity in organs such as lung, spleen, kidney, liver, heart, skeletal muscle, and small intestine were observed by biochemical method.
The results were as follow:
1. In the rats infected with 50 or 100 metacercariae of Clonorchis sinensis, the lysozyme activities of the liver, kidney, spleen, and skeletal muscle were increased throughout the experimental period.
The lysozyme activity of the small intestine was increased slightly only on the 10th day after infection and that of the lung was decreased throughout the entire experimental period.
2. In the rats infected with 200 metacercariae of Clonorchis sinensis, the lysozyme activities of the liver, the kidney, the spleen, and the skeletal muscle were markedly increased throughout the entire experimental period, and those of the lung, the heart and the small intestine were increased on the in 10th and 20th day after infection.
3. The lysozyme activity was increased in parallel with the number of metacercariae infected.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|